The expansion of CD4+CD28- T cells in patients with rheumatoid arthritis

Table 1 Frequency of CD4+CD28^- T cells in control group and in patients with RA

Subjects	CD4⁺CD28^- T cells (%)^a	P
Control group	1.40 (0.1–3.4)
Groups of RA patients
1) With limited joint manifestations	4.82 (3.71–10.95	0.001^b
2) With advanced joint involvement	7.05 (4.43–20.04)	0.005^c
3) With extra-articular manifestations	10.35 (4.19–36.60)	0.001^c

^aMedian (range). ^bvs control group. ^cvs RA patients with limited joint manifestations.

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