Figure 6

Contribution of tumor necrosis factor (TNF) to lipopolysaccharide (LPS) induction of tristetraprolin (TTP) in THP-1 cells. The cells were incubated with LPS (a) or TNF (b) in the absence or presence of blocking TNF antibody (infliximab [Remicade]), and TTP levels were measured at specific times. Results are expressed as percentage change from baseline expression (mean ± SE). Experiments were performed in duplicate.