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Table 2 Expression in vivo of tristetraprolin in volunteers

From: Regulation and localization of endogenous human tristetraprolin

Volunteer no.   Neutrophils Lymphocytes Monocytes
1 Baseline 16.5 (1.2) 18.8 (1.0) 15.6 (1.6)
  Peak 54.9 (2.0) 90.4 (8.8) 18.9 (2.4)
2 Baseline 15.6 (1.2) 9.9 (1.0) 23.2 (2.0)
  Peak 17.1 (3.6) 13.1 (1.2) 40.8 (4.3)
3 Baseline 9.7 (8.2) 4.2 (0.5) 20.8 (1.3)
  Peak 20.8 (1.4) 9.4 (2.3) 62.0 (29.0)
4 Baseline 13.6 (1.1) 6.0 (0.6) 16.6 (1.7)
  Peak 17.5 (1.1) 19.1 (1.8) 47.2 (1.6)
  1. Values are mean milliequivalents of soluble fluorescein (SE) (in thousands). Human subjects were infused with a bolus dose of lipopolysaccharide at T = 0. Blood was drawn at specific times before and after infusion, and the leukocytes were purified by dextran sedimentation. Expression of tristetraprolin was determined by flow cytometry.