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Figure 1 | Arthritis Research & Therapy

Figure 1

From: Specificity of T cells in synovial fluid: high frequencies of CD8+ T cells that are specific for certain viral epitopes

Figure 1

Staining of paired samples of peripheral blood and synovial fluidwith human leucocyte antigen (HLA)-peptide tetrameric complexes. Paired samplesof peripheral blood mononuclear cells (PBMCs; left column) and synovial fluidmononuclear cells (SFMCs; right column) from donors (a) RhA6, (b,c) RhA5 and (d) RhA7 were stained with a monoclonal antibody thatwas specific for CD8 and with (a, b) the A2/GLCTLVAML tetramer or (c,d) the B8/RAKFKQLL tetramer. The percentage frequency of CD8+ Tcells that reacted with the tetrameric complexes is shown; 50 000 live cellswere included in the analysis.

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