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Figure 5 | Arthritis Research & Therapy

Figure 5

From: Specificity of T cells in synovial fluid: high frequencies of CD8+ T cells that are specific for certain viral epitopes

Figure 5

The phenotype of RAKFKQLL-specific T cells in peripheral blood andsynovial fluid from patient RhA7. Samples of peripheral blood mononuclear cells(PBMCs; left column) and synovial fluid mononuclear cells (SFMCs; right column)were stained with anti-CD8, the B8/RAKFKQLL tetramer and with monocloncalantibodies specific for (a) CD38, (b) CD62L, (c) CD45RA,(d) CD45RO, (e) CD57 and (f) CD28. The percentagefrequency of CD8+ tetramer reactive cells that stain with thephenotypic markers are shown; 200000 live cells were included in the analysis.FITC, fluorescein isothiocyanate.

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