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Table 1 Levels of RANKL, osteoprotegerin (OPG), IL-6, soluble IL-6 receptor (sIL-6R), and soluble glycoprotein 130 (sgp130) in the bone marrow of rheumatoid arthritis and osteoarthritis patients

From: Unbalanced levels of bone resorption promoting factors in bone marrow from patients with rheumatoid arthritis in comparison to osteoarthritis

Patients

RANKL (pg/ml)

OPG (ng/ml)

OPG:RANKL ratio

IL-6 (pg/ml)

sIL-6R (ng/ml)

sgp130 (ng/ml)

sgp130:sIL-6R ratio

sIL-6R:IL-6 ratio

Rheumatoid arthritis

61 ± 50

9.9 ± 3.3

163:1

284 ± 370

33.7 ± 19

195 ± 111

5.8:1

118:1

Osteoarthritis

40 ± 34

12.4 ± 3.2

311:1

132 ± 76

16.7 ± 6.9

123 ± 55

7.3:1

126:1

Rheumatoid arthritis vs osteoarthritis

NS

P < 0.05

 

Not significant

P < 0.0002

P < 0.009

  
  1. NS, not significant.