Association of MHC and rheumatoid arthritis: HLA-DR4 and rheumatoid arthritis - studies in mice and men

Table 3 Combined analyses in 2 × 2 analyses of data in Table 1 and data on Swiss patients and controls given in Zanussi et al [8]

Test	Odds ratio	Significance^*	P	Heterogeneity^†	P ^‡
DQA-RA association	3.4	90.5	2E-21	1.35	0.51
SE association	4.1	102.0	5E-24	0.62	0.74
DQA-RA association in SE-positive	ND
DQA-RA association in SE-negative	1.5	1.7	0.19	1.2	0.54
SE association in DQ-RA-positive	2.9	12.7	0.0004	0.35	0.84
SE association in DQ-RA-negative	ND

ND, Not defined. ^* Significance for the deviation ofodds ratio from unity. ^† Heteroengeneity between the two setsof data. ^‡ Significance for the heterogeneity.

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