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Table 1 Presenting clinical features and prevalence of autoantibodies in rheumatoid factor positive rheumatoid arthritis (RF + RA), RF-negative RA (RF-RA), and nonRA patients

From: Rheumatoid arthritis associated autoantibodies in patients with synovitis of recent onset

 

RF + RA

RF - RA

Non RA

 

(n = 70)

(n = 36)

(n = 132)

Age

47 ± 12

44 ± 14

39 ± 13*

Female

44 (63)

27 (75)

87 (66)

Swollen joint count

13 ± 9

16 ± 10

2 ± 3*

CRP level

1.9 ± 1.9

1.9 ± 2.1

1.6 ± 2.4

Multiple erosions

12 (17)

7 (19)

7 (5)*

RF

70 (100)

0

17 (13)

ANA

25 (36)

10 (28)

30 (23)

ds-DNA

0

0

3(2)

Anti-SSA

5 (7)

2 (6)

7 (5)

Anti-SSB

2 (3)

1 (3)

2 (2)

Anti-RNP

3 (4)

0

3 (2)

Anti-Sm

0

0

2(2)

AFA

32 (46)

3 (8)

9 (7)

Anti-Sa

18 (26)

5(14)

3 (2)

Anti-CCP

38 (54)

5 (14)

12 (9)

AKA

26 (37)

1 (3)

21 (16)

Anti-RA-1

23 (33)

10 (28)

49 (37)

Anti-RA-33

2 (2)

0

1 (1)

  1. All values represent either number of patients (%), or means ± standard deviations. *P<0.01 compared with RA patients; P<0.01 compared with RF - RA and nonRA; P<0.01 compared with nonRA. CRP, C-reactive protein; ANA, antinuclear antibodies; AFA, antifilaggrin antibody; RNP, ribonucleoprotein; CCP, cyclic citrullinated peptide; AKA, antikeratin antibody.