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Table 1 Presenting clinical features and prevalence of autoantibodies in rheumatoid factor positive rheumatoid arthritis (RF + RA), RF-negative RA (RF-RA), and nonRA patients

From: Rheumatoid arthritis associated autoantibodies in patients with synovitis of recent onset

  RF + RA RF - RA Non RA
  (n = 70) (n = 36) (n = 132)
Age 47 ± 12 44 ± 14 39 ± 13*
Female 44 (63) 27 (75) 87 (66)
Swollen joint count 13 ± 9 16 ± 10 2 ± 3*
CRP level 1.9 ± 1.9 1.9 ± 2.1 1.6 ± 2.4
Multiple erosions 12 (17) 7 (19) 7 (5)*
RF 70 (100) 0 17 (13)
ANA 25 (36) 10 (28) 30 (23)
ds-DNA 0 0 3(2)
Anti-SSA 5 (7) 2 (6) 7 (5)
Anti-SSB 2 (3) 1 (3) 2 (2)
Anti-RNP 3 (4) 0 3 (2)
Anti-Sm 0 0 2(2)
AFA 32 (46) 3 (8) 9 (7)
Anti-Sa 18 (26) 5(14) 3 (2)
Anti-CCP 38 (54) 5 (14) 12 (9)
AKA 26 (37) 1 (3) 21 (16)
Anti-RA-1 23 (33) 10 (28) 49 (37)
Anti-RA-33 2 (2) 0 1 (1)
  1. All values represent either number of patients (%), or means ± standard deviations. *P<0.01 compared with RA patients; P<0.01 compared with RF - RA and nonRA; P<0.01 compared with nonRA. CRP, C-reactive protein; ANA, antinuclear antibodies; AFA, antifilaggrin antibody; RNP, ribonucleoprotein; CCP, cyclic citrullinated peptide; AKA, antikeratin antibody.