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Table 2 Association of autoantibodies with shared epitope (SE) alleles

From: Rheumatoid arthritis associated autoantibodies in patients with synovitis of recent onset

 

SE/x

SE/SE

*0401/*0101

All patients

   

RF

1.8

3.7*

8.7*

AFA

2.2*

5.1*

9.5*

Anti-Sa

2.0

7.1*

18.9*

Anti-CCP

2.0

5.0*

10.9*

AKA

1.4

3.1*

3.4*

RA patients

   

RF

1.8

2.7

5.3

AFA

2.2

4.9*

6.5*

Anti-SA

1.9

4.0*

10.6*

Anti-CCP

2.0

3.0

7.2*

AKA

1.4

2.9

3.3

  1. Numbers represent odds ratios for having each autoantibody associated with shared epitope alleles. SE/x, SE/SE, DRB *0401/*0101 were each compared with patients with no shared epitope alleles. *P<0.05 by Chi-square after Bonferroni adjustment for multiple comparison, RF, Rheumatoid factor; AFA, antifilaggrin antibody; CCP, cyclic citrullinated peptide; AKA, antikeratin antibody.