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Table 3 Diagnostic value of individual autoantibodies for rheumatoid arthritis

From: Rheumatoid arthritis associated autoantibodies in patients with synovitis of recent onset

 

Sensitivity

Specificity

PPV

NPV

Accuracy

RF

0.66

0.87

0.80

0.76

0.78

AFA

0.33

0.93

0.79

0.63

0.66

Anti-Sa

0.22

0.98

0.88

0.61

0.64

Anti-CCP

0.41

0.91

0.78

0.66

0.69

AKA

0.26

0.84

0.56

0.58

0.58

RF+ and one or more*

0.50

0.96

0.90

0.70

0.75

RF- and one or more*

0.31

0.73

0.26

0.77

0.63

  1. * Includes antifilaggrin antibody (AFA), anti-Sa, cyclic citrullinated peptide (anti-CCP) and antikeratin antibody (AKA). PPV, positive predictive value; NPV, negative predictive value; RF, rheumatoid factor.
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Arthritis Research & Therapy

ISSN: 1478-6362

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