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Table 1 Total number of cells in lymph nodes in DA and E3 naïve rats and rats 8 days after pristane injection

From: Differential gene expression in pristane-induced arthritis susceptible DA versus resistant E3 rats

  Total cell number (millions)
Cell type DA day 0* E3 day 0* Difference between DA and E3 on day 0** DA day 8 E3 day 8 Difference between DA and E3 on day 8**
Leucocytes 10 ± 1.5 8 ± 0.79 NC, P < 0.1 27 ± 3.6 45 ± 21 NC, P < 0.3
Granulocytes 0.034 ± 0.01 0.052 ± 0.01 D, P < 0.04 0.48 ± 0.14 0.92 ± 0.62 NC, P < 0.5
B cells 1.8 ± 0.64 2.3 ± 0.29 NC, P < 0.25 6.3 ± 1.2 24 ± 13 D, P < 0.03
αβ T cells 7.9 ± 0.7 5.4 ± 0.3 I, P < 0.02 20 ± 1.3 19 ± 2.8 NC, P < 1
CD4+/αβ T cells 6.2 ± 0.5 4.3 ± 0.2 MI, P < 0.08 14 ± 0.9 13 ± 1.7 NC, P < 0.3
CD8+/αβ T cells 2.2 ± 0.2 1.7 ± 0.1 NC, P < 0.2 6.1 ± 0.7 7.5 ± 1.4 NC, P < 0.3
γδ T cells 0.024 ± 0.013 0.038 ± 0.0086 MD, P < 0.1 0.048 ± 0.018 0.24 ± 0.16 D, P < 0.03
NK cells 0.095 ± 0.034 0.12 ± 0.01 NC, P < 0.4 0.46 ± 0.07 1.51 ± 1.0 NC, P < 0.2
NK T cells 0.054 ± 0.019 0.12 ± 0.024 D, P < 0.02 0.19 ± 0.035 2 ± 1.2 D, P < 0.03
  1. *Mean total cell number (in millions) ± standard deviation (SD) determined by fluorescence activated cell sorting (FACS) analysis. Data based on three DA and E3 naïve rats and three DA and E3 rats 8 days after pristane injection. **Difference in cell number: DA versus E3. P values calculated by Mann–Whitney nonparametric test. D, decrease; I, increase; MD, marginally decrease; MI, marginally increase; NC, no change.
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