Effective use of TNF antagonists

Table 1 Improved symptom control with disease progression

	Score
Parameter	Year 1	Year 2	Year 3	Outcome
Mean SJC	5.2	3.5	2.4	Reduced symptoms
Mean TJC	13.7	9.0	6.5	Reduced symptoms
Mean pain	22.4	13.4	11.1	Reduced symptoms
Mean Larsen index	5.6	12.3	16.9	Increased structural damage

SJC, swollen joint count (maximum score 44); TJC, tender joint count (maximum score 53). Data on file, Centocor, Inc., Malvern, PA, USA.

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