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Table 5 Logistic regression analysis of mild-to-moderate CAC versus severe CAC

From: Total calcium-sensing receptor expression in circulating monocytes is increased in rheumatoid arthritis patients with severe coronary artery calcification

  Pvalue for univariate model Pvalue for multivariate model
Age 0.59  
Gender 0.003 0.007
Weight 0.66  
Height 0.048 0.91
Body mass index 0.48  
Hypertension 1.00  
Hypercholesterolemia 0.29  
Diabetes 1.00  
Current smoker 1.00  
Methotrexate users 1.00  
Anti-TNFα users 1.00  
NSAIDs users 0.37  
Corticosteroid users 0.21  
Erosive arthritis 1.00  
RF and/or CCP antibodies 1.00  
hs-CRP 0.32  
TNFα 0.66  
DAS28-hs-CRP 0.01 0.73
Systolic blood pressure, mmHg 0.87  
Diastolic blood pressure, mmHg 0.12 0.42
Serum calcium 0.85  
Serum phosphate 0.09  
GFR-MDRD 0.03 0.08
Glycemia 0.71  
Total cholesterol, g/l 0.84  
LDL cholesterol, g/l 0.77  
HDL cholesterol, g/l 0.74  
Serum intact PTH 0.33  
Serum 25 OH Vitamin D 0.15 0.43
Hemoglobin 0.31  
White blood cell 0.57  
Neutrophils 0.69  
Monocytes 0.04 0.11
Surface CaSR expression 0.84  
Total CaSR expression 0.03 0.90
  1. Significant results are indicated in bold. CaSR, calcium-sensing receptor; hs-CRP, high-sensitivity C-reactive protein; PTH, parathyroid hormone; RF, rheumatoid factor; CCP, citrullinated cyclic protein; DAS28-hs-CRP, disease activity score 28-high-sensitivity C-reactive protein; TNFα, tumor necrosis factor alpha; NSAIDs, nonsteroidal anti-inflammatory drugs; GFR-MDRD, estimated glomerular filtration rate using the modification of diet in renal disease; LDL cholesterol, low-density lipoprotein; HDL cholesterol, high-density lipoprotein.