Serum biomarker levels in active spondyloarthritis (SpA) (n = 37) versus healthy controls (HC) (n = 20). Independent samples t-tests were performed. Data are represented as mean (standard error of the mean). *P <0.05. hs-CRP, high-sensitivity C-reactive protein; IL-6, interleukin-6; PTX-3, pentraxin-3; alpha-2-MG, alpha-2-macroglobulin; MMP-3, matrix metalloproteinase-3; VEGF, vascular endothelial growth factor.