Skip to main content
Figure 3 | Arthritis Research & Therapy

Figure 3

From: Expression and regulation of neurotrophic and angiogenic factors during human intervertebral disc degeneration

Figure 3

Cytokine regulation of neurotrophic factors NGF, BDNF and NT3 in human nucleus pulposus cells, SH-SY5Y cells and HDMEC cells. Neurotrophic factor mRNA expression in human nucleus pulposus (NP) cells stimulated by interleukin (IL)-1 (A), tumour necrosis factor alpha (TNFα) (B) and IL-6 (C). Neurotrophic factor mRNA expression in SH-SY5Y neuronal cells following cytokine stimulation (D). Neurotrophic factor mRNA expression in human dermal microvascular endothelial cells (HDMEC; endothelial cell line) following cytokine stimulation (E). *Statistical significance: P ≤ 0.05. BDNF, brain-derived neurotrophic factor; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; NGF, nerve growth factor; NT3, neurotrophin 3.

Back to article page

Arthritis Research & Therapy

ISSN: 1478-6362

Contact us