Table 2 Symptoms, associated disorders and prescribed drugs
Symptoms, n (%) | All cases n = 97 | Normal mucosa (Marsh stage 0) n = 39 | Lymphocytic enteritis (Marsh stage 1) n = 58 | P |
|---|---|---|---|---|
Widespread soft-tissue pain | 97 (100) | 39 (100) | 58 (100) | 1.000 |
Digestive complaints †| 97 (100) | 39 (100) | 58 (100) | 1.000 |
Fatigue | 88 (91) | 35 (90) | 53 (91) | 0.932 |
Sleep disturbances | 81 (83) | 29 (74) | 52 (89) | 0.087 |
Anxiety/depression | 64 (66) | 22 (56) | 42 (72) | 0.158 |
Skin problems ‡ | 48 (49) | 20 (51) | 28 (48) | 0.934 |
Foggy mind | 34 (35) | 14 (36) | 20 (34) | 0.941 |
Urinary urgency | 28 (29) | 10 (26) | 18 (31) | 0.729 |
Balance problems/dizziness | 27 (28) | 10 (26) | 17 (29) | 0.869 |
Chronic headaches ⊥ | 26 (27) | 5 (13) | 21 (36) | 0.021 |
Joint stiffness | 25 (26) | 9 (23) | 16 (28) | 0.794 |
Paraesthesias | 23 (24) | 9 (23) | 14 (24) | 0.902 |
Associated disorders , n (%) | ||||
Osteoporosis | 12 (12) | 2 (5) | 10 (17) | 0.144 |
TMJ disorder | 11 (11) | 5 (13) | 6 (10) | 0.959 |
Restless legs | 11 (11) | 3 (8) | 8 (14) | 0.547 |
Symptom duration, years, mean (SD) | ||||
Gastrointestinal symptoms | 29 (6) | 29 (5) | 29 (8) | 0.029 |
Extraintestinal symptoms | 9 (2) | 9 (2) | 9 (2) | 0.501 |
Prescribed drugs , n (%) | ||||
Analgesics * | 79 (81) | 34 (87) | 45 (78) | 0.344 |
Omeprazole | 76 (78) | 29 (74) | 47 (81) | 0.595 |
Antidepressants ⊥ | 65 (67) | 25 (64) | 40 (69) | 0.780 |
Pregabalin | 55 (57) | 19 (49) | 36 (62) | 0.275 |
Benzodiazepines/hypnotics | 55 (57) | 20 (51) | 35 (60) | 0.500 |
Antispasmodics/Antidiarrhoeals †| 37 (38) | 17 (38) | 33 (57) | 0.281 |
Laxatives | 13 (13) | 10 (26) | 27 (47) | 0.062 |