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Table 1 Association of PADI4 SNP (recessive model) with Sharp/van der Heijde score of hands at 5-year disease duration in ACPA-negative RA patients

From: Response to `Peptidyl arginine deiminase type IV (PADI4) haplotypes interact with shared epitope regardless of anti-cyclic citrullinated peptide antibody or erosive joint status in rheumatoid arthritis: a case control study'

Factor Beta (95% CI) Pvalue
rs2240340, PADI4 0.72 (0.08-1.36) 0.0287
HLA-DRB1 SE 0.36 (0.01-0.73) 0.0587
RF 0.54 (0.05-1.02) 0.0316
  1. ACPA, Anti-citrullinated peptide antibody; CI, Confidence interval; PADI4, Peptidyl arginine deiminase type IV; RA, Rheumatoid arthritis; RF, Rheumatoid factor; SE, Shared epitope; SNP, Single-nucleotide polymorphism.