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Figure 3 | Arthritis Research & Therapy

Figure 3

From: Heterogeneous expression pattern of interleukin 17A (IL-17A), IL-17F and their receptors in synovium of rheumatoid arthritis, psoriatic arthritis and osteoarthritis: possible explanation for nonresponse to anti-IL-17 therapy?

Figure 3

Retinoic acid receptor-related orphan receptor γt-positive cells in synovium. Immunohistochemistry showed an abundant nuclear expression of the IL-17-specific transcription factor retinoic acid receptor-related orphan receptor γt (RORγt) (shown in red) in synovial tissue biopsies (A). Immunofluorescence showed that RORγt-positive cells (red nuclei) in synovial tissue were indeed positive for interleukin 17A (IL-17A) (B) or IL-17F (C).

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Arthritis Research & Therapy

ISSN: 1478-6362

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