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Table 1 Demographic and clinical features a

From: Heterogeneous expression pattern of interleukin 17A (IL-17A), IL-17F and their receptors in synovium of rheumatoid arthritis, psoriatic arthritis and osteoarthritis: possible explanation for nonresponse to anti-IL-17 therapy?

 

Controls (n = 7)

RA (n = 11)

PsA (n = 15)

OA (n = 14)

Age, yr

47 (40 to 60)

49 (45 to 62)

48 (34 to 56)

68 (54 to 77)

Females, n (%)

2 (29)

7 (64)

7 (47)

10 (71)

Disease duration, mo

NA

18 (8 to 88)

41 (23 to 84)b

42 (13 to 72)c

Erosive disease, n (%)

NA

3/8 (38)

ND

ND

RF-positive, n/total (%)

NA

3/11 (27)

ND

ND

ACPA-positive, n (%)

NA

4/7 (57)

ND

ND

VAS GDA

NA

57 (55 to 85)

67 (54 to 75)

ND

TJC28, n

NA

9 (7 to 13)

2 (1 to 12)

ND

SJC28

NA

11 (6 to 14)

2 (1 to 12)

ND

ESR, mm/h

NA

23 (16 to 47)

34 (8 to 56)

ND

CRP, mg/L

NA

24.3 (12.0 to 37.0)

11.0 (4.7 to 18.0)

ND

DAS28

NA

5.46 (5.33 to 6.62)

4.67 (2.83 to 5.99)

ND

NSAID use, n (%)

NA

7 (64)

6 (40)

6 (67)d

MTX use, n (%)

NA

6 (55)

10 (67)

0 (0)

  1. aACPA, Anticitrullinated protein antibodies; CRP, C-reactive protein; DAS28, Disease Activity Score in 28 joints; ESR, Erythrocyte sedimentation rate; MTX, Methotrexate; NA, Not applicable; ND, Not determined; NSAID, Nonsteroidal anti-inflammatory drug; OA, Osteoarthritis; PsA, Psoriatic arthritis; RA, Rheumatoid arthritis; RF, Rheumatoid factor; SJC28, Swollen joint count of 28 joints; TJC28, Tender joint count of 28 joints; VAS GDA, Visual analogue scale (range from 0 to 100 mm) global disease activity. bn = 1, cn = 6, dn = 5 with no data available. Data are presented as median (interquartile range).