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Table 2 Standardized incidence ratios for each cancer according to type of rheumatic disease a

From: Comparison of cancer incidence among patients with rheumatic disease: a retrospective cohort study

Site of cancer RA SLE SSc DM PM
Breast O/E 10/12.509 4/5.883 0/1.653 0/0.492 0/0.282
SIR (CI) 0.799 (0.304 to 1.295) 0.68 (0.185 to 1.741) 0 (0 to 2.231) 0 (0 to 7.492) 0 (0 to 13.088)
Cervical O/E 4/3.786 7/1.635 0/0.47 0/0.136 0/0.085
SIR (CI) 1.056 (0.288 to 2.705) 4.282 (1.722 to 8.824) 0 (0 to 7.846) 0 (0 to 27.198) 0 (0 to 43.353)
Colorectal O/E 13/18.514 5/3.933 1/1.803 0/0.491 0/0.386
SIR (CI) 0.702 (0.32 to 1.084) 1.271 (0.413 to 2.967) 0.555 (0.014 to 3.09) 0 (0 to 7.518) 0 (0 to 9.55)
Endometrial O/E 0/1.883 0/0.742 0/0.238 2/0.066 0/0.044
SIR (CI) 0 (0 to 1.959) 0 (0 to 4.974) 0 (0 to 15.512) 30.529 (3.697 to 110.283) 0 (0 to 84.476)
Lung O/E 14/15.667 0/2.637 7/1.424 2/0.363 0/0.319
SIR (CI) 0.894 (0.489 to 1.499) 0 (0 to 1.399) 4.917 (1.977 to 10.131) 5.514 (0.668 to 19.917) 0 (0 to 11.546)
NHL O/E 8/2.462 5/0.675 1/0.242 1/0.071 0/0.049
SIR (CI) 3.387 (1.462 to 6.673) 7.408 (2.405 to 17.287) 4.141 (0.105 to 23.071) 14.088 (0.357 to 78.491) 0 (0 to 74.764)
Stomach O/E 15/22.625 3/5.027 2/2.236 1/0.614 1/0.473
SIR (CI) 0.663 (0.327 to 0.998) 0.597 (0.123 to 1.744) 0.898 (0.109 to 3.245) 1.629 (0.041 to 9.076) 2.113 (0.054 to 11.774)
Thyroid O/E 14/14.957 11/7.111 0/1.829 1/0.633 0/0.318
SIR (CI) 0.936 (0.446 to 1.426) 1.547 (0.633 to 2.461) 0 (0 to 2.017) 1.58 (0.04 to 8.805) 0 (0 to 11.601)
  1. aDM, dermatomyositis; E, expected cases; NHL, Non-Hodgkin’s lymphoma; O, observed cases; PM, polymyositis; RA, rheumatoid arthritis; SLE, systemic lupus erythematosus; SSc, systemic sclerosis. Numbers in parentheses represent the 95% confidence interval (CI). CIs in bold do not include 1. Data in bold are statistically significant.