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Table 5 Principal component analysis of cartilage tissue

From: Cytokine profiles in the joint depend on pathology, but are different between synovial fluid, cartilage tissue and cultured chondrocytes

Mediator Cluster
1 2 3 4 5
IL-1α 0.947     
TNFα 0.926     
OSM 0.914     
RANTES 0.912     
IL-10 0.835     
IL-13 0.814     
MCP1 0.745     
LIF 0.693     
Adiponectin   0.846    
HGF   0.789    
bFGF   0.664    
VEGF   0.610    
IL-1β    0.963   
IFNγ    0.933   
IL-6     0.967  
IL-8     0.945  
IL-4      0.690
Leptin      0.508
IL-1RA      −0.466
Eigenvalues 6.2 2.7 2.1 2.0 1.3
Variance explained (%) 33 14 11 11 7
Cronbach’s alpha 0.772 0.024 0.196 0.272 0.001
  1. bFGF, basic fibroblast growth factor; HGF, hepatocyte growth factor; IFNγ, interferon gamma; IL, interleukin; LIF, leukaemia inhibitory factor; MCP1, monocyte chemotactic factor 1; OSM, oncostatin M; RANTES, regulated upon activation normal T cell expressed and presumably secreted; TNFα, tumour necrosis factor alpha; VEGF, vascular endothelial growth factor.