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Table 5 Principal component analysis of cartilage tissue

From: Cytokine profiles in the joint depend on pathology, but are different between synovial fluid, cartilage tissue and cultured chondrocytes

Mediator

Cluster

1

2

3

4

5

IL-1α

0.947

    

TNFα

0.926

    

OSM

0.914

    

RANTES

0.912

    

IL-10

0.835

    

IL-13

0.814

    

MCP1

0.745

    

LIF

0.693

    

Adiponectin

 

0.846

   

HGF

 

0.789

   

bFGF

 

0.664

   

VEGF

 

0.610

   

IL-1β

  

0.963

  

IFNγ

  

0.933

  

IL-6

   

0.967

 

IL-8

   

0.945

 

IL-4

    

0.690

Leptin

    

0.508

IL-1RA

    

−0.466

Eigenvalues

6.2

2.7

2.1

2.0

1.3

Variance explained (%)

33

14

11

11

7

Cronbach’s alpha

0.772

0.024

0.196

0.272

0.001

  1. bFGF, basic fibroblast growth factor; HGF, hepatocyte growth factor; IFNγ, interferon gamma; IL, interleukin; LIF, leukaemia inhibitory factor; MCP1, monocyte chemotactic factor 1; OSM, oncostatin M; RANTES, regulated upon activation normal T cell expressed and presumably secreted; TNFα, tumour necrosis factor alpha; VEGF, vascular endothelial growth factor.