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Table 7 Principal component analysis of expanded chondrocytes

From: Cytokine profiles in the joint depend on pathology, but are different between synovial fluid, cartilage tissue and cultured chondrocytes

Mediator

Cluster

1

2

3

4

IL-4

0.980

   

IL-1β

0.976

   

Adiponectin

0.971

   

Leptin

0.963

   

TNFα

0.958

   

IL-1α

0.954

   

IL-7

0.954

   

IL-10

0.953

   

HGF

0.944

   

IFNγ

0.942

   

IL-13

0.940

   

IL-1RA

0.926

   

OSM

0.912

   

bFGF

0.845

   

IL-8

 

0.817

  

IL-6

 

0.788

  

RANTES

 

0.671

  

LIF

 

0.635

  

MCP1

 

0.541

  

VEGF

  

0.847

 

IL-6R

   

0.914

Eigenvalues

13.8

2.4

1.2

1.0

Variance explained (%)

66

11

6

5

Cronbach’s alpha

0.812

0.293

n.a.

n.a.

  1. bFGF, basic fibroblast growth factor; HGF, hepatocyte growth factor; IFNγ, interferon gamma; IL, interleukin; LIF, leukaemia inhibitory factor; MCP1, monocyte chemotactic factor 1; n.a., not available; OSM, oncostatin M; RANTES, regulated upon activation normal T cell expressed and presumably secreted; TNFα, tumour necrosis factor alpha; VEGF, vascular endothelial growth factor.