Skip to main content
Figure 3 | Arthritis Research & Therapy

Figure 3

From: Expansion of regulatory GITR+CD25low/-CD4+ T cells in systemic lupus erythematosus patients

Figure 3

CD4+CD25low/-GITR+cells from HC and SLE patients express comparable levels of CD62L . CD62L mRNA expression (fold decrease expressed in a base 2 logarithmic scale) in CD4+CD25low/-GITR+ and CD4+CD25highGITR- T cells over the respective naïve effector CD4+CD25-GITR- cell population, arbitrarily set equal to 1. The levels of mRNA expression in effectors from HC and SLE patients were similar. Expression level of CD62L mRNA in CD4+CD25-GITR- effector cells activated by 72-hour treatment with PMA plus ionomycin is also reported as control. Bars indicate mean ± SEM. ***P <0.001, according to Mann Whitney U test comparing expression in Treg cell population (CD4+CD25low/-GITR+ and CD4+CD25highGITR-) with that of the respective CD4+CD25-GITR- cell population. ###P <0.001, according to Mann-Whitney U test comparing expression in HC and SLE.

Back to article page