Figure 3From: Targeted exon sequencing fails to identify rare coding variants with large effect in rheumatoid arthritisRare variants of VSTM1 identified by exon sequencing. The seven nonsynonymous variants of VSTM1 that were validated by the Sanger sequencing method were primarily singletons driven from controls except for A33T (RA (n = 3), control (n = 5)). The four nonsynonymous variants of VSTM1 lie within the coding regions of the immunoglobulin-like domain.Back to article page