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Table 1 Characteristics of RA patients and controls included in targeted exon sequencing

From: Targeted exon sequencing fails to identify rare coding variants with large effect in rheumatoid arthritis

  RA cases (n = 1,217)* Controls (n = 717)*
Age of onset (mean ± SD years) 41.9 ± 12.8 35.1 ± 10.7
Disease duration (mean ± SD years) 9.9 ± 11.1 -
Female (%) 87.4 85.3
Rheumatoid factor (%) 97.8 -
Anti-cyclic citrullinated peptide autoantibodies (%) 98.1 -
  1. *Cryptic relatedness with duplicate or first-degree relatives using KING software, outlier (deviating >8 SEM on any of the five principal components), or samples with less than 80% of the data sequenced were removed. A total of 1,934 samples were included for further analysis. SD, standard deviation; SEM, standard error of the mean.