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Table 1 Proteins tested by mass spectrometry in matched synovial fluid and serum samples

From: Mass spectrometry assays of plasma biomarkers to predict radiographic progression of knee osteoarthritis

Protein

Protein symbol

Peptides, number

Synovial fluid

Serum

Aggrecan

ACAN

14

Y

N

Cartilage acidic protein 1

CRTAC1

10

Y

Y

Clusterin

CLU

8

Y

Y

Cartilage oligomeric matrix protein

COMP

15

Y

Y

Dickkopf 1 homolog

DKK1

6

N

N

Fatty acid binding protein 5

FABP5

2

Y

Y

Follistatin

FST

11

N

N

Group XV phospholipase A2

PLA2G15

8

N

N

Hepatocyte growth factor

HGF

1

Y

Y

Hyaluronan and proteoglycan link protein

HAPLN

13

N

N

Insulin-like growth factor-binding complex acid labile subunit

IGFALS

13

Y

Y

Kallistatin

SERPINA4

5

Y

Y

Lumican

LUM

5

Y

Y

Lysosomal phospholipase

ACP2

6

N

N

Matrix metalloproteinase 3

MMP3

10

Y

Y

Pigment epithelium derived factor

PEDF

12

Y

Y

Procollagen C-endopeptidase enhancer 1

PCOLCE

7

Y

Y

Protein S100-A16

S100A16

1

Y

Y

Semenogelin-2

SEMG2

2

Y

Y

Type 1 Collagen (α1, α2)

COL1A

3

Y

Y

Type 2 Collagen (α1)

COL2A1

1

Y

Y

Type 3 Collagen (α1)

COL3A1

1

Y

Y

Xaa-Pro dipeptidase

PEPD

14

N

N

  1. Y, yes; N, no.