Figure 2

Magnetic resonance imaging characterization of the intervertebral disc (IVD) of biglycan-deficient ( Bgn−/0) and wild type (WT) mice over time. T2-weighted images of the Bgn−/0 mouse IVD were acquired at months (A) 6, (B) 11, (C) 16 and (D) 18, and of WT mice IVD at month 16 of life (E). Boxes and arrows identify the spinal column level at vertebrae L1 to L2.