Histological evaluation in placebo, transplanted and wild type (WT) mice. Representative histological sections of Safranin-O (A-F) and Iba1 (G-I) immunostaining at the final follow-up period (12 weeks) from mice treated with placebo (A,B,G) or adipose mesenchymal stem cells (C,D,H), and from WT mice (E,F,I). Safranin-O staining is shown at two different magnifications (A,C,E and B,D,F, respectively). Scale bar: 500 μm (A-F) and 100 μm (G-I). Iba1, ion calcium binding protein.