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Figure 1 | Arthritis Research & Therapy

Figure 1

From: Hypoxia and vitamin D differently contribute to leptin and dickkopf-related protein 2 production in human osteoarthritic subchondral bone osteoblasts

Figure 1

Alteration of the expression of selective gene targets under hypoxia. Human osteoarthritis (OA) osteoblasts were incubated for 24 hours either under normoxia (Nox) or hypoxia (Hox; 2% O2). Vascular endothelial growth factor (VEGF) (A), Sirt1 (B) and transforming growth factor β1 (TGFbeta) (C). *P <0.05, statistically significant compared to Nox (n =4 to 6 experiments).

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