From: Serum sclerostin in high-activity adult patients with juvenile idiopathic arthritis
 | Patients with JIA(n=31) | Control participants(n=84) | P-value |
---|---|---|---|
Males/females (n) | 12/19 | 36/48 | 0.692 |
Age (yr) | 25.1 ± 6.1 | 23.8 ± 4.5 | 0.405 |
Height (cm) | 170.5 ± 9.8 | 173.3 ± 9.3 | 0.145 |
Weight (kg) | 68.0 ± 12.5 | 69.2 ± 12.5 | 0.884 |
BMI (kg/m2) | 23.4 ± 3.9 | 22.9 ± 3.0 | 0.435 |
Vertebral fractures (n) | 5 | 0 | <0.001 |
Nonvertebral fractures (n) | 6 | 0 | <0.001 |
Family hip fracture history (n) | 0 | 0 | Â |
Smoking (n) | 7 | 13 | 0.372 |
Alcohol abuse (n) | 0 | 0 | Â |
Glucocorticoids (n) | 12 | 0 | <0.001 |
Menarche (yr) | 13.1 ± 1.2 | 12.9 ± 1.1 | 0.994 |
Contraception in females (n) | 11 | 23 | 0.462 |
25(OH)D (nmol/L) | 54.3 | 2.4 | 0.029 |
(20.2 to 168.7) | (30.7 to 64.9) | ||
PTH (pmol/L) | 4.8 | 5.9 | 0.004 |
(1.3 to 8.8) | (4.7 to 7.6) | ||
Oestradiol (pmol/L) | 98.7 | 103.2 | 0.438 |
(18.4 to 541.1) | (56.4 to 260.3) |