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Table 2 Clinical characteristics of patients with juvenile idiopathic arthritis by sex a

From: Serum sclerostin in high-activity adult patients with juvenile idiopathic arthritis

  Men with JIA(n=12) Women with JIA(n=19) P-value
Age (yr) 21 26 0.079
(19.75 to 26.5) (20.5 to 32.8)
Height (cm) 178.8 ± 7.6 165.2 ± 7.0 <0.001
Weight (kg) 73.3 ± 11.7 64.6 ± 12.1 0.059
BMI (kg/m2) 22.9 ± 2.9 23.7 ± 4.5 0.559
Disease duration (yr) 11.0 ± 8.2 16.9 ± 9.4 0.087
Vertebral fractures (n) 3 2  
Nonvertebral fractures (n) 2 4  
Smoking (n) 3 4  
Glucocorticoids (n) 3 9 0.230
Menarche (yr)   13.1 ± 1.2  
Contraception (n)   11  
hsCRP (mg/L) 9.65 13.78 0.395
(5.84 to 44.78) (6.78 to 24.21)
DAS28 6.07 6.44 0.041
(5.63 to 6.52) (6.15 to 7.04)
ESR (mm/hr) 24.5 26.0 0.670
(17.0 to 54.0) (24.0 to 34.5)
Swollen joints (n) 11.0 12.0 0.263
(7.5 to 13.5) (9.0 to 18.3)
Tender joints (n) 13.5 17.0 0.038
(10.0 to 15.0) (12.3 to 21.5)
PGH (mm) 67.5 69.0 0.947
(60.0 to 74.5) (53.8 to 77.5)
Osteocalcin (μg/L) 24.3 14.3 0.016
(20.2 to 28.0) (11.3 to 23.0)
PINP (μg/L) 57.6 40.1 0.003
(46.3 to 85.6) (19.9 to 46.4)
βCTX-I (μg/L) 0.54 0.23 <0.001
(0.43 to 0.87) (0.14 to 0.36)
PTH (pmol/L) 4.08 4.80 <0.001
(1.73 to 6.05) (2.50 to 6.15)
Lumbar spine BMD (g/cm2) 1.018 1.075 0.392
(0.913 to 1.201) (1.012 to 1.221)
Total femur BMD (g/cm2) 0.938 0.877 0.073
(0.887 to 1.131) (0.764 to 0.916)
Femoral neck BMD (g/cm2) 0.934 0.875 0.092
(0.853 to 1.132) (0.805 to 0.948)
Distal radius BMD (g/cm2) 0.751 0.667 0.030
(0.677 to 0.792) (0.606 to 0.704)
  1. aDisplayed are numbers or means ± SD and/or medians and 75% CIs. BMD: Bone mineral density; BMI: Body mass index; βCTX-I: C-terminal telopeptide of collagen type I; DAS28: Disease Activity Score in 28 joints; ESR: Erythrocyte sedimentation rate; hsCRP: High-sensitivity C-reactive protein; JIA: Juvenile idiopathic arthritis; 25(OH)D: 25-hydroxyvitamin D3; PINP: Procollagen type I N-terminal propeptide; PTH: Parathyroid hormone; PGH: patient global health.