Serum sclerostin in high-activity adult patients with juvenile idiopathic arthritis

Table 4 Pearson correlation coefficients for the variables measured at baseline and during tumour necrosis factor α inhibitor treatment ^a

	GCs	Duration	Lumbar spine BMD	Femur neck BMD	Dkk1	Sclerostin	hsCRP	DAS28	ESR	Tender joint counts
Sex	0.226^b	0.311^c	0.074	0.350^c	0.281^c	−0.029	−0.124	0.280	0.085^c	0.211^b
GCs		0.130	0.274^c	0.391^d	0.291^c	0.229^b	0.229^b	0.416^d	0.330^c	0.323^c
Duration			0.176	−0.500^d	−0.021	0.010	0.100	0.192	0.100	0.104
Lumbar spine BMD				0.512^d	−0.106	−0.178	−0.055	−0.121	−0.075	−0.071
Femoral neck BMD					0.017	−0.154	−0.113	−0.270^b	−0.266^b	−0.116
Dkk1						0.026	0.402^d	0.113	0.244	0.071
Sclerostin							−0.011	0.317^c	0.023	0.332^c
hsCRP								0.318^c	0.751^d	0.089
DAS28									0.594^d	0.857^d
ESR										0.255^b

^aBMD: Bone mineral density; DAS28: Disease Activity Score in 28 joints; Dkk1: Dickkopf Wnt signalling pathway inhibitor 1; ESR: Erythrocyte sedimentation rate; GCs: Glucocorticoids; hsCRP: High-sensitivity C-reactive protein. ^bP <0.05; ^cP <0.005; ^dP <0.001.

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