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Table 5 Cluster analysis variables compared across clusters in the validation sample a

From: OMERACT-based fibromyalgia symptom subgroups: an exploratory cluster analysis

Measure

Cluster 1b(n = 116)

Cluster 2c(n = 154)

Cluster 3d(n = 100)

Cluster 4e(n = 108)

P-valuef

MFI physical fatigue

13.0 (3.9)

17.5 (2.3)

16.4 (2.7)

18.9 (1.8)

<0.0001

MOS-Sleep problems Index II

46.1 (15.9)

52.9 (16.3)

68.5 (14.8)

74.1 (12.3)

<0.0001

FIQ pain

4.8 (1.5)

7.1 (1.3)

6.7 (1.2)

8.5 (0.9)

<0.0001

MASQ

82.7 (18.1)

91.3 (21.3)

107.0 (17.1)

112.8 (19.5)

<0.0001

FIQ function

7.0 (4.8)

17.4 (5.2)

14.0 (5.2)

22.6 (3.5)

<0.0001

FIQ stiffness

5.4 (2.2)

7.5 (1.8)

6.7 (2.2)

8.9 (1.0)

<0.0001

GAD-7

5.0 (4.1)

5.0 (3.7)

14.2 (4.0)

13.0 (4.7)

<0.0001

PHQ-9

8.6 (4.1)

9.5 (3.2)

17.1 (4.5)

17.4 (4.3)

<0.0001

  1. aN = 478 total validation sample. Data are n (%). FIQ, Revised Fibromyalgia Impact Questionnaire; GAD-7, Generalized Anxiety Disorder 7-item scale; MASQ, Multiple Ability Self-report Questionnaire; MFI, Multidimensional Fatigue Inventory; MOS-Sleep Problems Index II, Medical Outcomes Study Sleep Scale; PHQ-9, Patient Health Questionnaire. bLow symptom intensity. cModerate symptoms, low negative mood. dModerate symptoms, higher negative mood and dyscognition. eHigh symptom intensity. fP-values are from the omnibus analysis of variance test across the four clusters. Pairwise comparisons between clusters also showed significant differences in all cases, except for the following: cluster 1 versus cluster 2 in regard to GAD-7 (P = 0.96) and PHQ-9 (P = 0.07) and cluster 3 versus cluster 4 with respect to PHQ-9 (P = 0.53).
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Arthritis Research & Therapy

ISSN: 1478-6362

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