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Table 1 Patient characteristics of the two cohorts a

From: CRP genotype and haplotype associations with serum C-reactive protein level and DAS28 in untreated early rheumatoid arthritis patients

Baseline Cohort 1 (N=180) Cohort 2 (N=135) P-value
Age, yr 55 (27 to 78) 52 (26 to 71) 0.11
Female sex 66%   65%   0.91
Disease duration, days 84 (42 to 162) 98 (48 to 175) <0.001
Rheumatoid factor-positive, % 72%   68%   0.54
Anti-CCP-positive, % 65%   60%   0.41
Tender joint count 11 (3 to 26) 9 (2 to 22) 0.07
Swollen joint count 8 (2 to 23) 8 (2 to 20) 0.41
Patient global assessment, mm 67 (13 to 98) 50 (10 to 91) <0.001
CRP, mg/L 14 (1 to 132) 20 (2 to 105) 0.04
DAS28 score 5.6 (3.8 to 7.7) 5.3 (3.2 to 7.1) 0.02
HAQ 1.1 (0.1 to 2.5) 1.0 (0 to 2.3) 0.02
Year 1      
CRP, mg/L 2 (0.5 to 19) 7 (0.7 to 33) <0.001
DAS28 score 2.0 (1.7 to 4.3) 2.0 (1.3 to 5.1) 0.13
  1. aValues are medians with 5% to 95% percentile values in parentheses, unless otherwise stated. CCP, Cyclic citrullinated peptide; DAS28, Disease Activity Score in 28 joints; HAQ, Health Assessment Questionnaire. Fisher’s exact test and the Mann-Whitney rank-sum test were used when appropriate.