Figure 4From: Local intra-articular injection of rapamycin delays articular cartilage degeneration in a murine model of osteoarthritisThe effect of rapamycin on collagen, type X alpha 1 (COL10A1) expression in articular cartilage. (A) Representative images of immunostaining for COL10A1 (green). Scale bar = 20 μm. (B) Quantification of COL10A1-positive cells in the cartilage was calculated. (C) Graph indicating quantitative RT-PCR for COL10A1 in dimethyl sulphoxide (DMSO)- and rapamycin-treated mice 8 and 12 weeks after destabilization of the medial meniscus (DMM) injury. ***P <0.001, **P <0.01.Back to article page