| NOAR | Leiden EAC | ||||||
---|---|---|---|---|---|---|---|---|
 | Total EIA population | 2010 ACR/EULAR positive cohort | Total EIA population | 2010 ACR/EULAR positive cohort | ||||
Model/predictor | HR | 95% CI | HR | 95% CI | HR | 95% CI | HR | 95% CI |
Unadjusted | Â | Â | Â | Â | Â | Â | Â | Â |
RF positive | 1.11 | 0.83 to 1.49 | 1.10 | 0.79 to 1.53 | 1.88 | 1.29 to 2.74 | 1.53 | 0.99 to 2.36 |
ACPA positive | 1.27 | 0.94 to 1.73 | 1.14 | 0.82 to 1.59 | 0.63 | 0.32 to 1.23 | 0.31 | 0.13 to 0.73 |
Both antibodies positive | 1.51 | 1.23 to 1.85 | 1.29 | 1.02 to 1.64 | 1.59 | 1.21 to 2.09 | 1.12 | 0.80 to 1.57 |
Age and sex adjusted | Â | Â | Â | Â | Â | Â | Â | Â |
RF positive | 1.05 | 0.78 to 1.41 | 1.10 | 0.79 to 1.54 | 1.45 | 0.99 to 2.13 | 1.54 | 0.99 to 2.37 |
ACPA positive | 1.40 | 1.03 to 1.91 | 1.42 | 1.02 to 1.99 | 0.96 | 0.48 to 1.90 | 0.71 | 0.30 to 1.68 |
Both antibodies positive | 1.38 | 1.12 to 1.69 | 1.25 | 0.99 to 1.59 | 1.82 | 1.38 to 2.40 | 1.83 | 1.29 to 2.60 |
Multivariate a | Â | Â | Â | Â | Â | Â | Â | Â |
RF positive | 1.11 | 0.82 to 1.51 | 1.22 | 0.87 to 1.72 | 1. 48 | 0.99 to 2.21 | 1.47 | 0.94 to 2.30 |
ACPA positive | 1.35 | 0.98 to 1.88 | 1.39 | 0.97 to 1.99 | 1.05 | 0.53 to 2.09 | 0.79 | 0.33 to 1.89 |
Both antibodies positive | 1.35 | 1.09 to 1.68 | 1.31 | 1.01 to 1.69 | 1.57 | 1.15 to 2.14 | 1.59 | 1.08 to 2.32 |