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Table 2 Mammalian sympathetic neurotransmitters and their receptors

From: The role of peripheral nerve fibers and their neurotransmitters in cartilage and bone physiology and pathophysiology

Neurotransmitters

Receptors

Neuropeptide genes

Neurotransmitter receptor genes

Catecholaminergic

   

Norepinephrine or noradrenaline (NA)

≤10−8 M: α 1a-, b-, d- adrenoceptors

 

ADRA1A, ADRA1B, ADRA1D

≤10-8 M: α 2a-, b-, c-adrenoceptors

 

ADRA2A, ADRA2B, ADRA2C

≥10−6 M: β1-, β2-, β3-adrenoceptors

 

ADRB1, ADRB2, ADRB3

Peptidergic

   

Vasoactive intestinal peptide (VIP)

VIP-1, VIP-2, and VIP/PACAP receptors

VIP

VIPR1, VIPR2

  1. PACAP, pituitary adenylate cyclase-activating polypeptide.