Altered microbiota associated with abnormal humoral immune responses to commensal organisms in enthesitis-related arthritis

Table 1 Patient population

Feature	Enthesitis-related arthritis	Controls
Number	25	13
Age, years, median, range	13.0, 7.0 to 19.0	13.0, 5.8 to 18.0
Male:female, number	11:14	6:7
Body mass index, median, range	20, 16 to 41	23.7, 14.0 to 43.0
Disease duration, years, median, range	2.4, 0 to 8.2	N/A
HLA-B27+, number	9/24 (38%)	0/3
Known inflammatory bowel disease, number	2 (8.0%)	0
Erythrocyte sedimentation rate, median, range	9, 3 to 56
Medications
None, number	7 (28%)	13 (100%)
Methotrexate alone, number	2 (8.0%)
Pentasa alone, number	1 (4.0%)
Anti-TNF +/− conventional DMARD	15 (60%)

DMARD, disease-modifying anti-rheumatic drug (methotrexate, leflunomide); TNF, tumor necrosis factor; N/A, not applicable.

ISSN: 1478-6362