Altered microbiota associated with abnormal humoral immune responses to commensal organisms in enthesitis-related arthritis

Table 2 Comparison of clinical and laboratory features of children in cluster 1 versus cluster 2

Feature	Cluster 1	Cluster 2	P-value
Number	8	17	N/A
Age, years, median, range	13, 7 to 18	13, 7.5 to 19	0.932
Male:female, number	1:7	13:4	0.007
Body mass index, median, range	20, 16 to 33	23, 16 to 41	0.374
Disease duration, years, median, range	1.6, 0 to 6.5	3, 0 to 8.2	0.238
HLA-B27+, number	3/8, 38%	6/16, 38%	1.000
Known inflammatory bowel disease, number	1, 12%	1, 5.9%	1.000
Erythrocyte sedimentation rate, number: median, range	7: 10, 6 to 50	13: 9, 3 to 56	0.536
Medications, number
None	2, 25%	5, 29%
Methotrexate alone	0	2, 12%
Pentasa alone	0	1, 5.9%
Anti-TNF +/− conventional DMARD	6, 75%	9, 53%

DMARD, disease-modifying anti-rheumatic drug; TNF, tumor necrosis factor; N/A, not applicable.

ISSN: 1478-6362