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Figure 5 | Arthritis Research & Therapy

Figure 5

From: Neurotrophins are expressed in giant cell arteritis lesions and may contribute to vascular remodeling

Figure 5

Sera and supernatant concentrations of NGF and BDNF from GCA patients and controls. (A) NGF and BDNF sera concentrations from patients with GCA (n = 30) compared to controls (n = 48) with a sera dilution of 1:100. (B) NGF TASMC-related supernatant concentration from GCA patients (n = 8) compared to controls (n = 8). Supernatants were collected when VSMC reached 80% confluence, between passages 3 and 5. Experiments were performed in duplicate, with three independent ELISA assays and data are presented as pg/mL. BDNF, brain-derived neurotrophic factor; ELISA, enzyme-linked immunosorbent assay; GCA, giant cell arteritis; NGF, nerve growth factor; TASMC, temporal artery VSMC; VSMC, vascular smooth muscle cell.

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Arthritis Research & Therapy

ISSN: 1478-6362

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