Skip to main content

Table 1 Clinical and biological findings in the study cohort patients with GCA

From: Neurotrophins are expressed in giant cell arteritis lesions and may contribute to vascular remodeling

Clinical characteristics GCA patients (Plasma study) N (%) GCA patients (IHC study) N (%) GCA patients (Cohort study) N (%)
Number of patients 30 22 42
General characteristics    
Age in years, median (range) 77 (60-92) 80.7 (73-89) 76.3 (60-92)
Sex, women/men 23/7 14/8 30/12
Systemic manifestations 15 (50) 17 (77) 33 (78.5)
Fever 9 (30) 4 (18) 13 (31)
Weight loss 15 (50) 12 (54.5) 20 (47.6)
Cranial symptoms 21 (70) 14 (63.6) 31 (73.8)
Headache 21 (70) 14 (63.6) 31 (73.8)
Jaw claudication 15 (50) 11 (50) 19 (45.2)
Scalp tenderness 14 (46.6) 12 (54.5) 21 (50)
Abnormal temporal arteries* 13 (43) 7 (32) 7 (16.6)
Cranial ischaemic events 9 (30) 8 (36) 11(26)
Permanent visual loss 1 (3) 3 (13.6) 2 (4.7)
Amaurosis fugax 6 (20) 8 (36) 11 (26)
Stroke 2 (6.6) 1 (4.5) 3 (7)
Polymyalgia rheumatica 7 (23) 7 (32) 10 (24)
Biological findings Mean ± SD Mean ± SD Mean ± SD
Erythrocyte sedimentation rate (mm/h) 85.8+/-25 84+/-28 77.8+/-26
C-reactive protein (mg/L) 102.2+/-70.3 92.6+/-66 86.2+/-78
Platelet count (x 109/L) 476+/-157 484+/-162 448+/-150
Haemoglobin (g/L) 11.5+/-1.6 12.2+/-1.4 11.8+/-1.7
  1. *Abnormal temporal arteries at physical examination (painful, swollen, indurated and/or with decreased or absent pulsation). GCA, giant cell arteritis; IHC, immunohistochemistry; SD, standard deviation.