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Table 1 Clinical and biological findings in the study cohort patients with GCA

From: Neurotrophins are expressed in giant cell arteritis lesions and may contribute to vascular remodeling

Clinical characteristics

GCA patients (Plasma study) N (%)

GCA patients (IHC study) N (%)

GCA patients (Cohort study) N (%)

Number of patients

30

22

42

General characteristics

   

Age in years, median (range)

77 (60-92)

80.7 (73-89)

76.3 (60-92)

Sex, women/men

23/7

14/8

30/12

Systemic manifestations

15 (50)

17 (77)

33 (78.5)

Fever

9 (30)

4 (18)

13 (31)

Weight loss

15 (50)

12 (54.5)

20 (47.6)

Cranial symptoms

21 (70)

14 (63.6)

31 (73.8)

Headache

21 (70)

14 (63.6)

31 (73.8)

Jaw claudication

15 (50)

11 (50)

19 (45.2)

Scalp tenderness

14 (46.6)

12 (54.5)

21 (50)

Abnormal temporal arteries*

13 (43)

7 (32)

7 (16.6)

Cranial ischaemic events

9 (30)

8 (36)

11(26)

Permanent visual loss

1 (3)

3 (13.6)

2 (4.7)

Amaurosis fugax

6 (20)

8 (36)

11 (26)

Stroke

2 (6.6)

1 (4.5)

3 (7)

Polymyalgia rheumatica

7 (23)

7 (32)

10 (24)

Biological findings

Mean ± SD

Mean ± SD

Mean ± SD

Erythrocyte sedimentation rate (mm/h)

85.8+/-25

84+/-28

77.8+/-26

C-reactive protein (mg/L)

102.2+/-70.3

92.6+/-66

86.2+/-78

Platelet count (x 109/L)

476+/-157

484+/-162

448+/-150

Haemoglobin (g/L)

11.5+/-1.6

12.2+/-1.4

11.8+/-1.7

  1. *Abnormal temporal arteries at physical examination (painful, swollen, indurated and/or with decreased or absent pulsation). GCA, giant cell arteritis; IHC, immunohistochemistry; SD, standard deviation.