The relationship of apolipoprotein B and very low density lipoprotein triglyceride with hyperuricemia and gout

Rasheed, Humaira; Hsu, Angela; Dalbeth, Nicola; Stamp, Lisa K; McCormick, Sally; Merriman, Tony R

doi:10.1186/s13075-014-0495-z

Arthritis Research & Therapy

Table 2 Fast protein liquid chromatography lipid measurements

From: The relationship of apolipoprotein B and very low density lipoprotein triglyceride with hyperuricemia and gout

	Polynesians
	NU median [25th-75th percentile]	HU median [25th-75th percentile]	Gout median [25th-75th percentile]	PNU vs. HU	PNU vs. Gout	PHU vs. Gout
Number	30	30	30
Total serum cholesterol	5.71 [4.33-6.47]	5.73 [5.03-6.54]	5.99 [5.25-6.41]	0.48	0.47	0.86
Total FPLC cholesterol	4.75 [3.52-5.47]	4.16 [3.72-4.81]	4.00 [3.18-4.43]	0.25	0.074	0.41
LDL cholesterol	2.83 [2.20-3.22]	2.45 [2.14-3.09]	2.45 [1.99-2.97]	0.42	0.11	0.40
HDL cholesterol	1.13 [0.84-1.35]	0.96 [0.79-1.00]	0.77 [0.70-1.06]	0.030	0.0052	0.17
Total serum Tg	1.87 [1.15-3.04]	2.32 [1.83-3.29]	2.49 [1.46-4.36]	0.058	0.060	0.93
Total FPLC Tg	1.41 [0.97-2.16]	1.55 [1.23-1.80]	1.71 [1.09-2.85]	0.34	0.17	0.46
VLDL Tg	0.57 [0.37-1.18]	0.80 [0.61-1.06]	1.01 [0.60-2.11]	0.24	0.023	0.10
VLDL Tg:Total Tg	0.45 [0.32-0.61]	0.51 [0.43-0.60]	0.65 [0.53-0.75]	0.44	0.0071	0.0011
Total apo B (μmol/L)	1.09 [0.93-1.85]	0.94 [0.79-1.13]	1.10 [0.92-1.26]	0.026	0.59	0.020
VLDL apo B (μmol/L)	0.044 [0.028-0.079]	0.072 [0.045-0.101]	0.061 [0.028-0.132]	0.048	0.32	0.92
VLDL apo B:Total apo B	0.040 [0.025-0.077]	0.072 [0.050-0.11]	0.051 [0.022-0.121]	0.001	0.19	0.40
VLDL Tg:VLDL apo B	12.49 [7.95-20.14]	11.74 [8.23-15.26]	19.44 [13.61-25.83]	0.74	0.042	0.0011
			Europeans
Number	30	30	30
Total serum cholesterol	5.56 [4.75-6.09]	5.60 [4.93-6.39]	5.11 [4.27-6.59]	0.77	0.37	0.36
Total FPLC cholesterol	4.18 [3.73-4.86]	4.01 [3.19-4.70]	4.19 [3.28-5.10]	0.21	0.70	0.50
LDL cholesterol	2.51 [2.06-2.97]	2.45 [1.86-2.83]	2.37 [1.83-3.59	0.46	0.68	0.75
HDL cholesterol	1.27 [1.21-1.57]	1.01 [0.79-1.21]	1.00 [0.89-1.10]	2.14E-05	0.0001	0.79
Total serum Tg	1.58 [1.05-2.00]	1.92 [1.50-2.80]	2.45 [1.70-2.90]	0.019	0.0008	0.21
Total FPLC Tg	1.11 [0.64-1.35]	1.15 [0.90-1.41]	1.57 [1.23-2.25]	0.17	0.0001	0.0021
VLDL Tg	0.36 [0.16-0.47]	0.47 [0.35-0.65]	0.84 [0.59-1.30]	0.008	1.84E-06	0.0010
VLDL Tg:Total Tg	0.32 [0.24-0.41]	0.43 [0.35-0.50]	0.68 [0.49-0.60]	0.0041	1.23E-06	0.0004
Total apo B (μmol/L)	1.31 [1.09-1.65]	1.06 [0.72-1.42]	1.36 [1.03-1.76]	0.036	0.88	0.053
VLDL apo B (μmol/L)	0.038 [0.021-0.072]	0.064 [0.035-0.103]	0.090 [0.062-0.125]	0.018	4.53E-05	0.041
VLDL apo B:Total apo B	0.032 [0.019-0.054]	0.063 [0.043-0.090]	0.069 [0.051-0.092]	0.0001	8.59E-06	0.37
VLDL Tg:VLDL apo B	8.33 [4.76-13.61]	8.62 [5.74-12.56]	10.45 [7.41-13.72]	0.92	0.16	0.16

All P values are calculated using the Wilcoxon-Mann-Whitney test. NU: normouricaemia; HU: hyperuricaemia; FPLC: fast protein liquid chromatography; LDL: low-density lipoprotein; HDL: high-density lipoprotein; Tg: triglyceride; VLDL: very low-density lipoprotein; apo B: apolipoprotein B.

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