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Table 2 Knee structural changes assessed by MRI in patients based on PainDETECT score

From: The presence of meniscal lesions is a strong predictor of neuropathic pain in symptomatic knee osteoarthritis: a cross-sectional pilot study

 

OA/NP- PainDETECT ≤12 n = 25

OA/NP+ PainDETECT 13-18 n = 9

OA/NP+ PainDETECT ≥19 n = 16

Pvalue♦

MRI cartilage volume (mm 3 )

    

Global knee

12,439 ± 2,451

12,181 ± 3,894

12,280 ± 2,414

0.347

 Femur

8,872 ± 1,799

8,998 ± 2,769

8,784 ± 1,950

0.381

 Condyle

5,873 ± 1,220

5,678 ± 1,784

5,825 ± 1,552

0.288

 Plateau

3,567 ± 907

3,183 ± 1,467

3,497 ± 727

0.395

Medial compartment

6,232 ± 1,258

5,919 ± 2,098

6,101 ± 1,473

0.333

 Femur

4,594 ± 884

4,602 ± 1,451

4,474 ± 1,103

0.288

 Condyle

3,094 ± 541

2,878 ± 912

3,043 ± 915

0.172

 Plateau

1,639 ± 516

1,317 ± 791

1,626 ± 524

0.424

Lateral compartment

6,207 ± 1,404

6,207 ± 1,404

6,180 ± 1,476

0.300

 Femur

4,278 ± 1,030

4,397 ± 1,415

4,309 ± 1,002

0.445

 Condyle

2,779 ± 768

2,800 ± 1,019

2,782 ± 798

0.496

 Plateau

1,928 ± 595

1,865 ± 766

1,870 ± 738

0.720

Meniscal extrusion (presence)

    

 Medial compartment

7 (28%)

3 (33%)

11 (69%)

0.006†

 Lateral compartment

1 (4%)

1 (11%)

4 (25%)

0.023†

Meniscal tears (presence)

    

 Medial compartment

14 (56%)

5 (56%)

10 (63%)

0.347†

 Lateral compartment

3 (12%)

1 (11%)

7 (44%)

0.011†

Bone marrow lesions (presence)

    

 Medial compartment

13 (54%)a

8 (89%)

10 (63%)

0.246†

 Condyle

4 (17%)a

1 (11%)

3 (19%)

0.447†

 Plateau

12 (50%)a

7 (78%)

10 (63%)

0.186†

 Lateral compartment

9 (38%)a

5 (56%)

7 (44%)

0.321†

 Condyle

1 (4%)a

0 (0%)

1 (6%)

0.395†

 Plateau

8 (33%)a

5 (56%)

10 (63%)

0.032†

Synovial membrane thickness (mm)

    

 Global

2.23 ± 0.66

2.32 ± 0.51

2.13 ± 0.52

0.427

 Medial compartment

2.27 ± 1.28b

2.14 ± 0.58

1.97 ± 0.42c

0.390

 Medial recess

2.02 ± 0.96d

1.91 ± 0.62

1.93 ± 0.82c

0.399

 Medial suprapatellar bursa

2.89 ± 1.57e

2.73 ± 1.00f

2.13 ± 0.68e

0.111

 Lateral compartment

2.21 ± 0.75

2.47 ± 0.68

2.19 ± 0.73

0.402

 Lateral recess

1.90 ± 0.64a

2.07 ± 0.76

2.15 ± 0.55c

0.027

 Lateral suprapatellar bursa

2.64 ± 1.42b

2.96 ± 1.15g

2.26 ± 1.18

0.228

Synovial effusion (ml)

11.22 ± 7.74

14.40 ± 10.3

12.40 ± 6.40

0.202

  1. Results are shown as mean ± standard deviation (SD) unless otherwise indicated. P values were assessed using the ♦ Jonckheere-Terpstra test for trend, and the †Cochran-Armitage trend test. a, n = 24; b, n = 22; c, n = 15; d, n = 21; e, n = 12; f, n = 6; g, n = 8. MRI, magnetic resonance imaging; OA, osteoarthritis; NP, neuropathic pain; n, number of participants.
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Arthritis Research & Therapy

ISSN: 1478-6362

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