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Table 2 Knee structural changes assessed by MRI in patients based on PainDETECT score

From: The presence of meniscal lesions is a strong predictor of neuropathic pain in symptomatic knee osteoarthritis: a cross-sectional pilot study

  OA/NP- PainDETECT ≤12 n = 25 OA/NP+ PainDETECT 13-18 n = 9 OA/NP+ PainDETECT ≥19 n = 16 Pvalue♦
MRI cartilage volume (mm 3 )     
Global knee 12,439 ± 2,451 12,181 ± 3,894 12,280 ± 2,414 0.347
 Femur 8,872 ± 1,799 8,998 ± 2,769 8,784 ± 1,950 0.381
 Condyle 5,873 ± 1,220 5,678 ± 1,784 5,825 ± 1,552 0.288
 Plateau 3,567 ± 907 3,183 ± 1,467 3,497 ± 727 0.395
Medial compartment 6,232 ± 1,258 5,919 ± 2,098 6,101 ± 1,473 0.333
 Femur 4,594 ± 884 4,602 ± 1,451 4,474 ± 1,103 0.288
 Condyle 3,094 ± 541 2,878 ± 912 3,043 ± 915 0.172
 Plateau 1,639 ± 516 1,317 ± 791 1,626 ± 524 0.424
Lateral compartment 6,207 ± 1,404 6,207 ± 1,404 6,180 ± 1,476 0.300
 Femur 4,278 ± 1,030 4,397 ± 1,415 4,309 ± 1,002 0.445
 Condyle 2,779 ± 768 2,800 ± 1,019 2,782 ± 798 0.496
 Plateau 1,928 ± 595 1,865 ± 766 1,870 ± 738 0.720
Meniscal extrusion (presence)     
 Medial compartment 7 (28%) 3 (33%) 11 (69%) 0.006†
 Lateral compartment 1 (4%) 1 (11%) 4 (25%) 0.023†
Meniscal tears (presence)     
 Medial compartment 14 (56%) 5 (56%) 10 (63%) 0.347†
 Lateral compartment 3 (12%) 1 (11%) 7 (44%) 0.011†
Bone marrow lesions (presence)     
 Medial compartment 13 (54%)a 8 (89%) 10 (63%) 0.246†
 Condyle 4 (17%)a 1 (11%) 3 (19%) 0.447†
 Plateau 12 (50%)a 7 (78%) 10 (63%) 0.186†
 Lateral compartment 9 (38%)a 5 (56%) 7 (44%) 0.321†
 Condyle 1 (4%)a 0 (0%) 1 (6%) 0.395†
 Plateau 8 (33%)a 5 (56%) 10 (63%) 0.032†
Synovial membrane thickness (mm)     
 Global 2.23 ± 0.66 2.32 ± 0.51 2.13 ± 0.52 0.427
 Medial compartment 2.27 ± 1.28b 2.14 ± 0.58 1.97 ± 0.42c 0.390
 Medial recess 2.02 ± 0.96d 1.91 ± 0.62 1.93 ± 0.82c 0.399
 Medial suprapatellar bursa 2.89 ± 1.57e 2.73 ± 1.00f 2.13 ± 0.68e 0.111
 Lateral compartment 2.21 ± 0.75 2.47 ± 0.68 2.19 ± 0.73 0.402
 Lateral recess 1.90 ± 0.64a 2.07 ± 0.76 2.15 ± 0.55c 0.027
 Lateral suprapatellar bursa 2.64 ± 1.42b 2.96 ± 1.15g 2.26 ± 1.18 0.228
Synovial effusion (ml) 11.22 ± 7.74 14.40 ± 10.3 12.40 ± 6.40 0.202
  1. Results are shown as mean ± standard deviation (SD) unless otherwise indicated. P values were assessed using the ♦ Jonckheere-Terpstra test for trend, and the †Cochran-Armitage trend test. a, n = 24; b, n = 22; c, n = 15; d, n = 21; e, n = 12; f, n = 6; g, n = 8. MRI, magnetic resonance imaging; OA, osteoarthritis; NP, neuropathic pain; n, number of participants.
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Arthritis Research & Therapy

ISSN: 1478-6362

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