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Figure 1 | Arthritis Research & Therapy

Figure 1

From: Green tea polyphenol treatment is chondroprotective, anti-inflammatory and palliative in a mouse posttraumatic osteoarthritis model

Figure 1

Epigallocatechin 3-gallate administration slows progression in early and midstage osteoarthritis in mice that underwent surgical destabilization of the medial meniscus. Mice underwent sham surgery or surgical destabilization of the medial meniscus (DMM), and cartilage specimens were treated with vehicle or epigallocatechin 3-gallate (EGCG). Safranin O stains and Osteoarthritis Research Society International (OARSI) scores of mice at 4 weeks (A and B) and 8 weeks (C and D) following surgery are shown (*P < 0.05 by analysis of variance; n = 6/group). Arrowheads indicate the areas of cartilage fibrillation or erosion, and arrows indicate loss of Safranin O staining.

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Arthritis Research & Therapy

ISSN: 1478-6362

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