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Figure 3 | Arthritis Research & Therapy

Figure 3

From: Green tea polyphenol treatment is chondroprotective, anti-inflammatory and palliative in a mouse posttraumatic osteoarthritis model

Figure 3

Epigallocatechin 3-gallate administration reduced the degradation of aggrecan in the articular cartilage matrix. Immunohistochemical staining of cleaved aggrecan (NITEGE) and relative staining intensity in the articular cartilage matrix of mice that underwent sham operations or surgical destabilization of the medial meniscus (DMM) that were treated with vehicle or epigallocatechin 3-gallate (EGCG) at 4 weeks (A and B) and 8 weeks (C and D) following surgery (*P < 0.05 by analysis of variance; n = 6/group). Scale bar = 100 μM. (E) Representative staining of tissue sections with isotype control (rabbit immunoglobulin G (IgG)).

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Arthritis Research & Therapy

ISSN: 1478-6362

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