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Figure 4 | Arthritis Research & Therapy

Figure 4

From: Green tea polyphenol treatment is chondroprotective, anti-inflammatory and palliative in a mouse posttraumatic osteoarthritis model

Figure 4

Epigallocatechin 3-gallate administration reduced matrix metalloproteinase 13 levels in articular cartilage. Immunohistochemical staining of matrix metalloproteinase 13 (MMP-13) and percentage of MMP-13-positive cells in the articular cartilage of mice that underwent sham operations or surgical destabilization of the medial meniscus (DMM) that were treated with vehicle or epigallocatechin 3-gallate (EGCG) at 4 weeks (A and B) and 8 weeks (C and D) following surgery (*P < 0.05 by analysis of variance; n = 6/group). Scale bar = 100 μM. (E) Representative staining of tissue sections with isotype control (rabbit immunoglobulin G (IgG)).

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