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Figure 5 | Arthritis Research & Therapy

Figure 5

From: Green tea polyphenol treatment is chondroprotective, anti-inflammatory and palliative in a mouse posttraumatic osteoarthritis model

Figure 5

Epigallocatechin 3-gallate administration reduced ADAMTS5 levels in the articular cartilage. Immunohistochemical staining of A disintegrin and metalloproteinase with thrombospondin motifs 5 (ADAMTS5) and percentage of ADAMTS5-positive cells in the articular cartilage of mice that underwent sham operations or surgical destabilization of the medial meniscus (DMM) that were treated with vehicle or epigallocatechin 3-gallate (EGCG) at 4 weeks (A and B) and 8 weeks (C and D) following surgery (*P < 0.05 by analysis of variance; n = 6/group). Scale bar = 100 μM. (E) Representative staining of tissue sections with isotype control (rabbit immunoglobulin G (IgG)).

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