Skip to main content

Table 3 Correlation of substance P and CGRP with IL-1β, TNF-α and IL-10 in synovial fluid of patients with developmental dysplasia of the hip a

From: Increasing expression of substance P and calcitonin gene-related peptide in synovial tissue and fluid contribute to the progress of arthritis in developmental dysplasia of the hip

  

Correlation of SF neuropeptide levels

Group

Neuropeptide

With IL-1β

With TNF-α

With IL-10

Moderate DDH

 

R

P-value

R

P-value

R

P-value

 

SP

0.19

0.30

0.41

<0.05*

0.33

0.08

 

CGRP

0.10

0.64

0.40

<0.05*

0.69

<0.01*

Severe DDH

       
 

SP

0.45

<0.05*

0.48

<0.05*

0.39

<0.05*

 

CGRP

0.37

0.07

0.47

<0.01*

0.14

0.46

  1. aCGRP, Calcitonin gene-related peptide; DDH, Developmental dysplasia of the hip; IL, Interleukin; R, Correlation index; SF, Synovial fluid; SP, Substance P; TNF, Tumor necrosis factor. *A two-sided P-value <0.05 indicates a significant correlation with the corresponding neuropeptide in each column.