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Table 1 Synthetic peptides (SP) used in this study

From: Separate and overlapping specificities in rheumatoid arthritis antibodies binding to citrulline- and homocitrulline-containing peptides related to type I and II collagen telopeptides

Type I collagen

Sequence

Abbreviation

SP112

biotin

SAG FDF SFL PQP PQE KAH DGG RYY Cit A

CitI

SP132

biotin

SAG FDF SFL PQP PQE KAH DGG RYY Hcit A

HcitI

SP66

 

-- --- --- --- --E KAH DGG RYY Cit A

CitI

SP135

 

-- --- --- --- --E KAH DGG RYY Hcit A

HcitI

Type II collagen

  

SP86

biotin

GID MSA FAG LGP REK GPD PLQ YM Cit A

CitII

SP109

biotin

GID MSA FAG LGP REK GPD PLQ YM Hcit A

HcitII

SP41

 

--- --- --- --- -EK GPD PLQ YM Cit A

CitII

SP136

 

--- --- --- --- -EK GPD PLQ YM Hcit A

HcitII

  1. The peptides represent different parts of the carboxy-terminal telopeptide of the α1 chain of human type I or II collagen, each containing citrulline (Cit) or homocitrulline (Hcit) as indicated (for other amino acids, the one-letter symbols are used).