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Table 2 Sensitivity and specificity of citrulline and homocitrulline inhibition-ELISA assays for separating RA patients from healthy controls

From: Separate and overlapping specificities in rheumatoid arthritis antibodies binding to citrulline- and homocitrulline-containing peptides related to type I and II collagen telopeptides

Test

Sensitivity

Specificity

Anti-CCP

0.54

1.00a

Anti-MCV

0.57

1.00a

CitI

0.47

0.96

HcitI

0.22

0.96

CitII

0.41

0.94

HcitII

0.19

0.96

  1. aPositivity in CCP or MCV was considered as excluding factor in controls. Anti-CCP, anti-cyclic citrullinated protein; anti-MCV, anti-mutated citrullinated vimentin; Cit, citrulline; Hcit, homocitrulline.
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Arthritis Research & Therapy

ISSN: 1478-6362

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